Fahimtar Narrowband UVB Phototherapy

Jiyya na zabi don psoriasis, vitiligo, da eczema

Narrowband UVB Phototherapy - The Basics

"Narrowband" UVB ya zama phototherapy t saboda yana ba da mafi girman adadin mafi girman raƙuman raƙuman haske na UV, yayin da rage girman raƙuman ruwa masu lahani. 

na al'ada "Broadband" Fitilolin UVB suna fitar da haske a cikin faffadan kewayon sama da bakan UVB, gami da duka tsayin raƙuman warkewa na musamman don maganin cututtukan fata, da ɗan gajeren zangon da ke da alhakin kunar rana (erythema). Yin kunar rana yana da fa'idar warkewa mara kyau, yana ƙara haɗarin cutar kansar fata, yana haifar da rashin jin daɗi na haƙuri, kuma yana iyakance adadin UVB na warkewa da za a iya ɗauka.  

"Narrowband" Fitilolin UVB, a gefe guda, suna fitar da haske akan ɗan gajeren kewayon raƙuman raƙuman raƙuman raƙuman ruwa waɗanda aka tattara a cikin kewayon warkewa kuma kaɗan a cikin kewayon kunar rana, suna amfani da “tabo mai daɗi” tsakanin su biyun kusan 311 nm. Don haka UVB-Narrowband ya fi aminci da inganci fiye da UVB-Broadband, amma yana buƙatar ko dai tsawon lokacin jiyya ko kayan aiki tare da ƙarin kwararan fitila don cimma matsakaicin adadin, wanda ke kan ɗan farawar fata mai laushi bayan jiyya, wanda aka sani da “sub-erythema” . Samfuran UVB-Narrowband na Solarc suna da kari na “UVB-NB” a cikin lambar ƙirar, kamar 1780UVB-NB. Samfuran UVB-Broadband na Solarc suna da ƙari “UVB” kawai, kamar 1740UVB. "Narrowband UVB" Philips Lighting na Holland ne ya haɓaka kuma ana kuma san shi da: Narrow Band UVB, UVB Narrowband, UVB‑NB, NB‑UVB, TL/01, TL-01, TL01, 311 nm, da dai sauransu, (inda "01" shine lambar phosphor na Philips da aka saka a cikin lambobi na UVB-Narrowband kwan fitila).

Kuma don ƙarin bayani: 

Fahimtar Narrowband UVB Phototherapy

"Narrowband" UVB (UVB-NB) ya zama phototherapy magani na zabi ga psoriasis, vitiligo, atopic dermatitis (eczema), da sauran photoresponsive fata cuta. Fahimtar fa'idodin "Narrowband" UVB tare da na al'ada "Broadband" UVB phototherapy yana buƙatar fahimtar haske da hanyoyin da yake tasiri.

Bakan na gani na gani radiation (haske) ya ƙunshi daban-daban raƙuman raƙuman ruwa na "haske" jere daga 100 nanometers (nm) a cikin ultraviolet (UV) kewayon zuwa 1 millimeter (mm) a cikin infrared (IR). Hasken da ake iya gani yana tafiya daga kusan 380 nm (violet) zuwa 780 nm (ja) kuma ana kiran su "launi" da muke gani da idanunmu. Ultraviolet ba ya iya gani kuma ya tashi daga 380 nm zuwa 100 nm, kuma an ƙara raba shi zuwa UVA (315-380 nm), UVB (280-315 nm), da UVC (100-280 nm).

SIFFOFI A yana nuna irin ƙarfin “hasken” na halitta yana isa saman duniya bayan an tace da yanayin duniya. 'Yan Adam sun samo asali ne don fallasa duk waɗannan tsayin raƙuman ruwa, don haka fatarmu ta haɓaka martani don amfani da haske mai fa'ida (Vitamin D) da kuma kare mu daga wuce gona da iri (layin fata na gado da tanning). "UVB Narrowband" ana haskakawa a 311 nm kuma yana faruwa ta halitta a cikin hasken rana, amma ba da yawa ba. Yanayin duniya yana tace kusan dukkan hasken da bai wuce kusan nm 300 ba.
fahimtar narrowband uvb phototherapy
narrawband uvb phototherapy

Matsakaicin tsayi daban-daban na "haske" yana haifar da tasiri daban-daban akan kayan. An yi nazarin matakai masu mahimmanci da yawa a kimiyance don tantance gudunmawar dangi na kowane tsayin daka ga tsarin da aka yi nazari. Ana amfani da zane-zanen da aka sani da “bakan aikin” don bayyana waɗannan alaƙa. Mafi girman “hanzarin bakan aikin”, mafi girman tsarin aiwatar da wannan tsayin.

An yi nazarin bakan aikin don psoriasis1,2 don sanin cewa mafi yawan raƙuman raƙuman warkewa shine 296 zuwa 313 nm. Kamar yadda aka nuna a SIFFAR B, Fitilolin UVB-Broadband na al'ada sun rufe wannan kewayon kuma an yi amfani da su cikin nasara fiye da shekaru 60.

An kuma yi nazarin nau'in aikin "ƙona rana" na fatar ɗan adam, wanda aka fi sani da "erythema".11 Erythema yana mamaye ƙananan raƙuman ruwa (kasa da 300 nm) na kewayon UVB. Abin takaici, fitilun UVB-Broadband na al'ada suna samar da adadi mai yawa na "haske" a cikin wannan kewayon erythemogenic. Waɗannan tsayin igiyoyin suna haifar da ƙonawa kuma suna da ƙarancin jiyya. Menene ƙari, farkon ƙonawa yana iyakance adadin UVB3 kuma erythema abu ne mai haɗari ga ciwon daji na fata. Har ila yau Erythema yana haifar da rashin jin daɗi na majiyyaci, wanda zai iya hana wasu marasa lafiya su sha magani. Yankin launin toka mai launin toka a ciki Hoto C yana ba da wakilcin hoto na babban abun ciki na erythemogenic na UVB-Broadband.

uvbbroadband erythema fahimtar maƙarƙashiya uvb phototherapy

"Don haka me yasa ba za a haɓaka tushen haske wanda ke samar da mafi yawan abubuwan da yake samarwa a cikin nau'in aikin psoriasis ba kuma yana rage haske a cikin aikin erythema?"

uvbnarrowband erythema fahimtar maƙarƙashiya uvb phototherapy

A ƙarshen 1980's, Philips Lighting na Holland ya ƙera irin wannan fitilar, wanda aka sani da fitilar "TL-01" ko "UVB Narrowband". Karamin yankin inuwa mai launin toka a ciki KYAUTA D yana nuna cewa fitilun UVB-Narrowband suna da ƙarancin fitowar erythemogenic ( yuwuwar kunar rana) fiye da fitilun UVB-Broadband na al'ada. Wannan yana nufin cewa za a iya ba da ƙarin maganin UVB kafin erythema ya faru, kuma tun da erythema abu ne mai haɗari ga ciwon daji na fata, waɗannan sababbin fitilu ya kamata su kasance masu ƙarancin carcinogenic don sakamakon warkewa iri ɗaya.4,5,6,7. Bugu da ƙari kuma, kuma yana da mahimmanci ga nasarar da gida UVB-Narrowband phototherapy ya shaida, ya zama mafi yiwuwa cewa ana sarrafa cutar ba tare da kai ga matakin erythemogenic ba.9,10, wanda koyaushe yana da matsala tare da maganin UVB-Broadband. Yana da ban sha'awa a lura cewa kololuwar UVB-Narrowband yana da kusan sau goma sama da na UVB-Broadband, don haka tushen sunan "Narrowband".

Binciken da aka yi kwanan nan ya tabbatar da waɗannan binciken kuma sun ƙaddara cewa UVB-Narrowband yana da ƙarancin konewa da kuma tsawon lokacin gafara fiye da UVB-Broadband. Idan aka kwatanta da PUVA (hasken Psoralen + UVA-1), UVB-Narrowband yana da ƙarancin sakamako masu illa kuma ya maye gurbinsa a yawancin lokuta.8.

Ɗaya daga cikin lahani na UVB-Narrowband shine, saboda matsakaicin matsakaicin sashi yana iyakancewa ta farkon farkon erythema, kuma UVB-Narrowband ba shi da erythemogenic fiye da UVB-Broadband, ana buƙatar lokaci mai tsawo. Ana iya rama wannan ta hanyar ƙara yawan kwararan fitila a cikin na'urar4,5,6,7. Alal misali, dangane da Solarc's home phototherapy bayan tallace-tallace masu biyo baya don UVB-Broadband, 4-bulb 1740UVB yana ba da lokutan jiyya masu dacewa; alhali ga UVB-Narrowband, 8-bulb 1780UVB-NB zaɓi ne na kowa. Matsakaicin ka'idar yuwuwar erythemogenic na UVB-Broadband zuwa UVB-Narrowband yana cikin kewayon 4:1 zuwa 5:1.

Sauran cututtuka irin su vitiligo, eczema, mycosis fungoides (CTCL), da sauransu da yawa kuma an yi nasarar magance su tare da UVB-Narrowband, gabaɗaya don dalilai guda ɗaya kamar yadda aka bayyana a sama don psoriasis.

Wani fa'ida mai ban sha'awa na UVB-Narrowband shine wataƙila mafi kyawun nau'in fitilar fitila don yin Vitamin D (SIFFOFI E) a cikin fatar mutum, don amfani a maimakon hasken rana na halitta (wanda ya haɗa da UVA mai cutarwa), ko kuma ga waɗanda ba za su iya shan isasshen bitamin D (Allunan) na baki ba saboda matsaloli a cikin hanji. Batun Vitamin D ya sami kulawar kafofin watsa labarai da yawa kwanan nan, kuma saboda kyawawan dalilai. Vitamin D yana da mahimmanci ga lafiyar ɗan adam, amma duk da haka mutane da yawa suna da rashi, musamman waɗanda ke zaune a manyan latitudes, nesa da ma'aunin duniya. Akwai ƙara shaida cewa Vitamin D yana ba da kariya ga ci gaban cututtuka masu yawa, ciki har da ciwon daji (nono, colorectal, prostate), cututtuka na zuciya da jijiyoyin jini, sclerosis mai yawa, osteomalacia, osteoporosis, nau'in ciwon sukari na 1, rheumatoid arthritis, hauhawar jini, da damuwa. Don ƙarin bayani, da fatan za a ziyarci waɗannan shafukan yanar gizon: Vitamin D Phototherapy FAQ & Fitila don Vitamin D.

uvbnarrowband bitamind fahimtar kunkuntar uvb phototherapy

Babban ra'ayi a cikin al'ummar dermatology shine cewa UVB-Narrowband zai maye gurbin UVB-Broadband a matsayin zaɓi na magani, musamman don maganin hoto na gida. Wannan yana da goyan baya a fili ta hanyar Solarc Systems' yanayin tallace-tallacen kayan aikin hoto na gida, tare da siyar da na'urorin UVB-NB yanzu sun zarce tallace-tallacen UVB-BB da kusan 100:1. Samfuran UVB-Narrowband na Solarc suna da kari na “UVB-NB” a cikin lambar ƙirar, kamar 1780UVB-NB. Samfuran UVB-Broadband na Solarc suna da ƙari “UVB” kawai, kamar 1740UVB.

Solarc Systems na son gode wa mutanen kirki a Philips Lighting don haɓaka layin samfurin UVB-Narrowband, da kuma taimaka wa da yawa daga cikinmu a duk duniya sarrafa matsalolin fata cikin aminci da inganci. lura: Ƙididdiga da aka yi amfani da su a cikin wannan takarda wakilci ne a sauƙaƙe. An samo lanƙwan UVB-Broadband daga Solarc/SolRx 1740UVB kuma UVB-Narrowband an samo shi daga Solarc/SolRx 1760UVB‑NB.

Muna ƙarfafa ku don ƙara bincika wannan muhimmin batu.

References:

1 PARRISH JA, JAENICKE KF (1981) Action Spectrum don phototherapy na psoriasis. J zuba jari Dermatol. 76 359
2 FISCHER T, ALSINS J, BERNE B (1984) Bakan aikin Ultraviolet da kimanta fitilu na ultraviolet don warkar da psoriasis. Int. J. Dermatol. 23 633
3 BOER I, SCHOTHORST AA, SUURMOND D (1980) UVB phototherapy na psoriasis. Dermatologica 161 250
4 VAN WEELDEN H, BAART DE LA FAILLE H, YOUNG E, VAN DER LEUN JC, (1988) Wani sabon ci gaba a UVB phototherapy na psoriasis. Jaridar Burtaniya na Dermatology 119
5 KARVONEN J, KOKKONEN E, RUOTSALAINEN E (1989) 311nm UVB fitilu a cikin maganin psoriasis tare da tsarin Ingram. Acta Derm Venereol (Stockh) 69
6 JOHNSON B, GREEN C, LAKSHMIPATHI T, FERGUSON J (1988) Ultraviolet radiation phototherapy don psoriasis. Amfani da sabon kunkuntar band UVB fitila mai kyalli. Proc. Yuro na 2. Photobiol. Congr., Padua, Italy
7 GREEN C, FERGUSON J, LAKSHMIPATHI T, JOHNSON B 311 UV phototherapy - Magani mai mahimmanci ga psoriasis. Sashen Nazarin fata, Jami'ar Dundee
8 TANEW A, RADAKOVIC-FIJAN S, SC
HEMPER M, HONIGSMANN H (1999) Narrowband UV-B phototherapy vs photochemotherapy a cikin jiyya na plaque-type psoriasis. Arch Dermatol 1999; 135: 519-524
9 WALTERS I, (1999) Suberythematogenic kunkuntar band UVB ya fi tasiri fiye da UVB na al'ada a cikin maganin psoriasis vulgaris. J Am Acad Dermatol 1999;40:893-900
10 HAYKAL KA, DESGROSEILLIERS JP (2006) Shin Raka'o'in Gida na kunkuntar Ultraviolet B zaɓi ne mai yuwuwa don Ci gaba ko Kulawa da Cututtukan fata masu ɗaukar hoto? Jaridar Magungunan Cutaneous & Surgery, Juzu'i na 10, Fitowa ta 5: 234-240
11 Erythema reference mataki bakan da daidaitaccen erythema kashi ISO-17166: 1999 (E) | CIE S 007/E-1998
12 Action Spectrum don Samar da Previtamin D3 a cikin Fata na Mutum CIE 174: 2006